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SMC1A 抗体

This anti-SMC1A antibody is a 兔 单克隆 antibody detecting SMC1A in WB 和 IF. Suitable for 人.
产品编号 ABIN7270614
发货至: 中国

Quick Overview for SMC1A 抗体 (ABIN7270614)

抗原

See all SMC1A 抗体
SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

适用

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宿主

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克隆类型

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单克隆

标记

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This SMC1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    SMC1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human SMC1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

    别名

    SMC1A

    背景

    Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB,Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Protein phosphorylation,SMC1A

    分子量

    143kDa

    基因ID

    8243

    UniProt

    Q14683

    途径

    Stem Cell Maintenance
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